Lucrări Științifice Publicate / Acceptate cu mulțumiri la proiectul TM-Vector

Etapa 2023

1. Craciun BF, Clima L, Bostiog DI, Silion M, Calin M, Peptanariu D, Pinteala M. Multilayer gold nanoparticles as nonviral vectors for targeting MCF-7 cancer cells. Biomater Adv. 2023 Jan;144:213201; https://doi.org/10.1016/j.bioadv.2022.213201

2. Vasincu IM, Apotrosoaei M, Lupascu F, Iacob AT, Giusca SE, Caruntu ID, Marangoci NL, Petrovici AR, Stanciu GD, Tamba BI, Profire BS, Focsa AV, Pinteala M, Profire L. Complexes of Ibuprofen Thiazolidin-4-One Derivatives with β-Cyclodextrin: Characterization and In Vivo Release Profile and Biological Evaluation. Pharmaceutics. 2023 Oct 19;15(10):2492; https://doi.org/10.3390/pharmaceutics15102492

3. Bostiog DI, Natalia Simionescu N, Coroaba A, Marinas IC, Chifiriuc MC, Gratiela Gradisteanu Pircalabioru G, Maier SS, Pinteala M. Multi-Shell Gold Nanoparticles Functionalized with Methotrexate: A Novel Nanotherapeutic Approach for Improved Antitumoral and Antioxidant Activity and Enhanced Biocompatibility. Drug Delivery, Submission ID: 236177022

4. Cristina Mariana Uritu, Cristina Al-Matarneh, Denisse Bostiog, Adina Coroaba, Vlad Ghizdovat, Silviu Filipiuc, Natalia Simionescu, Cipriana Stefanescu, Valentin Nastasa, Bogdan Tamba, Stelian Maier and Mariana Pinteala Surface-modified gold nanoparticles: A step toward structural-functional hybrid PET/SPECT radiopharmaceuticals. Journal of Materials Chemistry B, în etapa de recenzie ( https://submissions.rsc.org/tracker/TB-ART-11-2023-002654)

6. Bostiog Denisse-Iulia, Nastasa Valentin, Al-Matarneh Maria Cristina, Peptanariu Dragos, Mares Mihai, Pasca Sorin-Aurelian, Bostanaru-Iliescu Andra-Cristina, Craciun Bogdan Florin, Maier Stelian Sergiu, Pinteala Mariana. Simple yet versatile conjugation and decoration strategy to produce nanoparticulate gene vectors. In vitro and in vivo evidence of their functionality and safety in use. HELIYON-D-23-53295 (https://www2.cloud.editorialmanager.com/heliyon/default2.aspx)

6. O.E. Carp, M. Pinteala, A. Arvinte. Electrodeposition of Au nanoparticles on 2D layered materials and their applications in electrocatalysis of nitrite. În evaluare la Nano Materials Science, manuscript ID: NMS-2023-0176

Cerere Brevet de Invenţie nr. A/00143/2023 cu titlul: “Procedeu de obţinere a agregatelor supramoleculare de nanoparticule de aur compacte, cu spectru larg de absorbtie in domeniul vizibil, cu aplicatii in fototermie”, Autori: Ursu Elena-Laura, Sardaru Monica-Cornelia, Ursu Cristian, Rotaru Alexandru.

 Participări conferințe / simpozioane cu mulțumiri la proiectul TM-Vector - 2023

1. Ioan-Andrei Dascalu, Manuela Calin, Cristina Mariana Uritu, Mariana Pinteala. Design and Characterization of Nanocarriers for Gene Therapy based on Polycations as Polyplexes. The 12th World Gene Convention-2023 (WGC-2023), 9-11 Ianuarie 2023, Sapporo, Japonia – prezentare orala.

2. Denisse-Iulia Bostiog, Natalia Simionescu, Bogdan Florin Craciun, Mariana Pinteala. Methotrexate-functionalized multi-shell gold nanoparticles for drug delivery applications. Conferinta XXXIIIth Edition of the International Congress of Apollonia University of Iasi. 02-02.03.2023 – prezentare orala.

3. D.I. Bostiog, C. M. Uritu, C. M. Al-Matarneh, A. Coroaba, N. Simionescu, V. Ghizdovat, S. I. Filipiuc, B. I. Tamba, C. Stefanescu3, V. Nastase, M. Pinteala. Innovations in Cancer Imaging and Therapy: The Role of Nanoparticles and Radiotracers. STEPI12 - Polyimides & High Performance Polymers, 4-7.06.2023, Montpellier, France – prezentare orala.

4. Adrian Fifere, Irina Rosca, Ioana-Andreea Turin Moleavin, Alexandra Sarghi, Mariana Pinteala. Magnetic nanoparticles as carriers for antibiotics and antioxidants that interact synergistically. 2nd International Chemistry Conference – CHEMEET 2023, 26-28.06.2023, Madrid, Spania, virtual conference – prezentare orala.

5. Narcisa Marangoci, Alexandra Sarghi, Ioana-Andreea Turin-Moleavin, Adrian Fifere. Organotellurides as generators of free radicals. Study by electronic spin resonance spectroscopy. 2nd International Chemistry Conference – CHEMEET 2023, 26-28.06.2023, Madrid, Spania, virtual conference – poster.

Etapa 2022

1. Petreni A, Iacobescu A, Simionescu N, Petrovici AR, Angeli A, Fifere A, Pinteala M, Supuran CT. Carbonic Anhydrase inhibitors bearing organotelluride moieties as novel agents for antitumor therapy. Eur J Med Chem. 2022 Oct 3;244:114811. doi: 10.1016/j.ejmech.2022.114811 .

2. Dimofte A, Simionescu N, Petrovici A-R, Spiridon I. Probiotic Properties of Weissella confusa PP29 on Hibiscus sabdariffa L. Media. Fermentation. 2022; 8(10):553. https://doi.org/10.3390/fermentation8100553.

3. Condurache M-I, Petrovici A-R, Simionescu N, Profire B-S, Confederat L-G, Bujor A, Miron A, Profire L. Simultaneous Determination of Glibenclamide and Silymarin Released from Chitosan Microparticles by HPLC-ESI-MS Technique: Method Development and Validation. Pharmaceutics. 2022; 14(10):2164. https://doi.org/10.3390/pharmaceutics14102164.

 Participări conferințe / simpozioane cu mulțumiri la proiectul TM-Vector - 2022

1. Keynote speaker: Mariana Pinteala, Non-Viral Vectors-Based Polycations as Polyplexes for Gene Therapy. Design and Characterization. International Chemistry Conference, June 27-29, 2022, CEST.

2. Keynote speaker: Lilia Clima, Cationic Polymers Enclosed in Supramolecular Architectures Aimed for Nucleic Acid Delivery International Chemistry Conference, June 27-29, 2022, CEST.

3. Adina Arvinte, Multimetallic Nanostructures for Electrochemical Sensing Applications, 19th International Conference on Nanosciences and Nanotechnologies (NANOTEXNOLOGY 2022), Thessaloniki, Grecia, 5 – 8 iulie 2022

4. B.F. Craciun, D. Peptanariu, M. Pinteala. Novel PEI-β-CD functionalized gold nanoparticles as non-viral vectors for in vitro targeting of MCF-7 tumoral cells. XXXVIth National Chemistry Conference (CNCHIM-2022), Calimanesti – Caciulata, Valcea, Romania, 04-07 October 2022; Oral presentation

5. D. I. Bostiog, N. Simionescu, M. Pinteala. Multi-shell gold nanoparticles functionalized with methotrexate for targeted therapy of breast cancer; 14th International Conference on Physics of Advanced Material (IPCAM-14), Dubrovnik, Croatia; 8-15 September 2022. Oral presentation.

6. D. I. Bostiog, B. F. Craciun, E. L. Ursu, D. Peptanariu, M. Pinteala. Investigations on the layer by layer multi-shell gold nanoparticles functionalization for the development of effective non-viral gene vectors; 7th International Congress on Biomaterials and Biosensors (BIOMATSEN), Mugla, Turcia; 22-28 April 2022. Poster

7. D. I. Bostiog, C.M. Al-Matarneh, D. Peptanariu, M. Pinteala. Investigations on the layer by  layer multi-shell gold nanoparticles functionalization for the development of effective non-viral gene vectors; Ediția a XXXVI-a a Conferinței Naționale de Chimie, CNChim-2022,  Călimănești-Căciulata, România; 4-8 October 2022. Poster

8. D. Bejan, S. Shova, I. Rosca, A.I. Sandu, N.L. Marangoci; “Synthesis, structures and characterization of novel N-hetrerocyclic ligands”; Ediția a XXXVI-a a Conferinței Naționale de Chimie, CNChim-2022,  Călimănești-Căciulata, România; 4-8 October 2022. Poster

Etapa 2021

M.C. Sardaru, N.L. Marangoci, S. Shova, D. Bejan. Novel Lanthanide (III) Complexes Derived from an Imidazole-Biphenyl-Carboxylate Ligand: Synthesis, Structure and Luminescence Properties. Molecules, 2021, 26(22), 6942; https://doi.org/10.3390/molecules26226942

1. M.C. Sardaru, I. Rosca, S. Morariu, E.L. Ursu, R. Ghiarasim, A. Rotaru. Injectable Thixotropic β–Cyclodextrin–Functionalized Hydrogels Based on Guanosine Quartet Assembly. Int. J. Mol. Sci. 2021, 22(17), 9179; https://doi.org/10.3390/ijms22179179

 Participări conferințe / simpozioane cu mulțumiri la proiectul TM-Vector - 2021

5. D. Peptanariu. Vectori non-virali de tip stea pentru transfectie. Conferinta Cercetarii Stiintifice din Academia Romana (CCSAR-2021), Bucuresti, 22-23 noiembrie 2021; conferință plenară.

4. O. E. Carp, M. Pinteala, A. Arvinte. Evaluation of antioxidant properties using electrochemistry combined with in vitro peroxidation and reducing assays. 6th International Congress on Biomaterials and Biosensors (BIOMATSEN), Oludeniz, Turkey, 17-23 October 2021; prezentare orală.

3. A. Fifere, I.-A. Turin-Moleavin, A.-L. Lungoci, I. Rosca, A. Iacobescu, A.R. Petrovici, A. Coroaba, M. Pinteala. Hybrid nanostructured systems based on metal oxides with magnetic and antioxidant properties for biomedical applications. Polymer Science and Composite Materials, prerioada 5-7 Iulie, 2021. Barcelona, Spania; prezentare orală.

2. L. Clima, B. Craciun, D. Peptanariu, M. Pinteala. Supramolecular squalene based self-assembled entities as promising non-viral vectors for gene delivery. International Conference of Polymer Science and Composite Materials “Polymer Connect”, Barcelona, Spania, 05-07 iulie. 2021; comunicare orală.

1. M. Pinteala. Biomedical applications of polymer-coated metallic nanoparticles. Polymer Science and Composite Materials, prerioada 5-7 Iulie, 2021, Barcelona, Spania; key note presentation.