 |
The project leading to this application has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 667387 |
 |
|
|
|
|||
|
The project leading to this application has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 667387 |
|
|
|
|
|||
|
During the last implementation period of the SupraChem Lab two important trainings including team building events have been organised (02.05.2018 - 05.05.2018 and 25 - 27.09.2019) within ICMPP for the SupraChem Lab Team. Except for these two major events seven (7) other trainings on targeted topics have been set up in order to develop the knowhow and experience of the group.
The 5th SupraChem Lab training event
The May 2018 trainers were:
The 5th SupraChem Lab training event Agenda
The 6th SupraChem Lab Project Training
The 6th SupraChem Lab training have brought in the group the expertise of two prestigious scientists: Prof. Ullrich Scherf director of the Institute for Polymer Technology at the Bergische Universität: he graduated in chemistry in 1983 from the Friedrich Schiller University in Jena.
He then completed his doctorate in polymer chemistry (including macromolecular chemistry) in 1988. In the meantime, he was on a research stay at the Tbilisi State University in 1987. He then worked until 1989 as a research assistant at the Institute for Animal Physiology of the Saxon Academy of Sciences under Heinz Penzlin . From 1990 to 1992 he was a fellow of the Association of the Chemical Industry at the Max Planck Institute for Polymer Researchin Mainz under Klaus Müllen . He was then head of the institute until 2000. In 1996 Scherf habilitated at the Johannes Gutenberg University Mainz in organic chemistry. In 2000 he became a professor of polymer chemistry at the University of Potsdam. In 2002 he accepted a professorship for macromolecular chemistry at the University of Wuppertal. In 2006 Scherf organized a summer school at the Indian Institute of Science in Bangalore.
The 6th SupraChem Lab training and team building event due to it special significance (last official training organised within the SuprChem Lab project) was organise in a different manner than the previous one. The first day was dedicated to the presentation of the SupraChem Lab team and of the facility of InteCentru (the host of the SupraChem Lab team). Fruitful discussions with the trainers have already started from this stage.
The 6th SupraChem Lab Project Training Agenda
Intensive course of cell biology, histology and cell pathology Prof. Hermenean is a prestigious researcher in histology and cell pathology that have some prestigious publications in the field as well as a strong experience in projects (including COST TD0901 “Hypoxia sensing, signalling and adaptation”) and patenting (Patent European: “Pharmaceutical composition useful for preventing and treating liver disease, comprises oil isolated from Silybum marianum seed”, Patent Number: WO2013124700-A2; HU201300110-A1). Monday, 11.06.2018 (9.30 - 13.30) Cell biology and histology, I Training event in Applications of Mass Spectrometry in Protein Characterization 19.06.2018 Dr. Costel C. Darie Associate Professor, Department of Chemistry & Biomolecular Science Clarkson University, 2015;
Prof. Darie currently focusing on proteomics investigation of various bodily fluids (sera, saliva, breast milk) for identification of biomarker signatures which are indicative of disease and/or disorder detection, or progression. In one of our projects, we focus on biomarker discovery for early detection of autism spectrum disorder and neurodevelopmental disorders (i.e. Fragile X syndrome, Smith-Lemli-Opitz syndrome). In a different project, we focus on studying depression and post-traumatic stress disorder. We also focus on early detection of the onset of breast cancer. We also use preoteomics for identification and characterization of protein post-translational modifications and of protein-protein interactions, as well as for deciphering signal transduction pathways using a combination of mass spectrometry and proteomics. In one such project, we focus on Tumor Differentiation Factor (TDF) and Jumping Translocation Breakpoint (JTB), two proteins with ubiquitous (JTB) or specific (TDF) distribution within particular cells within the body.
Training Events in the framework of the H2020 projects: A training event dedicated to high performance instruments for the identification of medical threats in different disease was organized with the support of three European Projects H2020 projects H2020-MSCA-RISE-2014 TROPSENSE (ref. 645758); H2020-MSCA-RISE-2017 bTB-Test (ref. 777832) coordinate by Dr. Radu Ionescu and H2020-WIDESPREAD 2-2014 SupraChem Lab (ref. 667387). The trainers were team members of the two RISE project with prestigious experience in addressing complex mechanism for the vention or tritmant of specia deses: Detailed Agenda
Training on Carbonic Anhydrase Inhibitors As Emerging Agents For The Treatment And Imaging Of Hypoxic Tumors
Training event in Computational Chemistry
Training Program: 11:15 - 12.30 Lecture of Philip Gillespie (Imperial College London): Designing and Engineering of Sequence-Specific microRNA Electrochemical Biosensors for Cancer Diagnostics
Training on the etiopathogenic mechanism, detection, diagnosis and the therapeutic approach of different forms of epidermolysis bullosa Prof Cristina Has UNIVERSITÄTSKLINIKUM FREIBURG, Klinik für Dermatologie Molekulare Dermatologie, Germany, was invited in the framework of Romanian Mobility Grant and on 25.11 – 01.12.2019 the SupraChem Lab Management Team have organised a joint action together with collaborators from the "Al. I. Cuza" University, Iaşi, Romania , “Gr T Popa” University of Medicine and Pharmacy and ”St. Mary” Pediatric Emergency Hospital Iasi Romania, in the conference room of P. Poni, Institute of Macromolecular Chemistry. The program of the meeting in ICMPP was:
|
|
Training performed by Dr Cristina Iojoiu, Directeur de Recherche, CNRS, LEPMI (Laborator d'electrochimie si fisico chimie des materiales si interfate) -Grenoble-INP, Francea, 16-17.11.2017
Dr. Cristina Iojoiu made a training on Electrolytes polymères pour les piles à combustible, accumulateurs lithium, cellules solaires à colorant. Due to renovation works in the institute, the training was made in the library of Petru Poni Institute of Macromolecular Chemistry.
Fourth SupraChem Lab training event 17.09.2017 - 19.09.2017 The second training event organised during the second reporting period (training no 4 of the project) was organised between 17.09.2017 - 19.09.2017 in the library of ICMPP. The initial idea, as suggested during the review meeting by Dr Argiris LASKARAKIS, was actually to organise practically a workshop were the members of the SupraChem lab to meet with several research personalities and to share research results. Unfortunately we could not organise at this level for 2017 due to the resignations of Dr. Barboiu and the fact that Prof Abadie the new SupraChem Lab ERA CHAIR has started his new position with 01.09.2017. Also the conference hall of ICMPP was blocked due to an important renovation project that is implementing in ICMPP.
The meeting Agenda 
Third Suprachem Lab indoor training 31.05.2017 - 01.06.2017 The training was performed by two experienced researchers from Fraunhofer-Institut für Biomedizinische Technik (IBMT), Germany:
The Training Agenda
On the last day of the training (02.06.2017) a team building event was organised, giving the opportunity to the members of the SupraChem Lab group to have open discussion with the two researchers from Germany
Training performed by Prof. Marc J.M. Abadie, University of Montpellier, France, 28.02 – 01.03.2017 Prof. Marc JM Abadie was invited to give advance training on UV/EB Curing-Principle, 3D Structures, Coatings and Thin Film Technologies between 28.02 – 01.03.2017. The training was divided in 8 sections organised during two days 9.30 -12.30 the Conference Room of ICMPP and with extend participation. In the afternoon individual discussions with the members of the SupraChem Lab group were organised in IntelCentre meeting room.
Training performed by Dr. Alice Cristina Mija Associate Professor HDR at University of Nice Sophia Antipolis, France, 07-10.11.2016
The training was organised by the SupraChem Lab management team in IntelCentre at P. Poni Institute of Macromolecular Chemistry between 07-10.11.2016 on the topics:
Training performed by Professor Cristina Has - UNIVERSITÄTSKLINIKUM FREIBURG, Klinik für Dermatologie Molekulare Dermatologie, Germany, 31.10.2016 Prof Cristina Has was invited in the framework of Romanian Mobility Grant and on 31.X.2016 the SupraChem Lab Management Team have organised a joint action together with collaborators from the "Al. I. Cuza" University, Iaşi, Romania , “Gr T Popa” University of Medicine and Pharmacy and ”St. Mary” Pediatric Emergency Hospital Iasi Romania, in the conference room of P. Poni, Institute of Macromolecular Chemistry.
The Second SupraChem Lab indoor training 25-27.09.2016 The second SupraChem Lab indoor training was organised together with the first SuparChem Lab Management Meeting. The training was performed by three experienced researchers from prestigious EU Institutions and by the SupraChem Lab ERA CHAIR:
September Training Agenda 
First SupraChem Lab indoor training 05-06.05.2016 The training was performed by several experienced researchers from prestigious EU Institutions:
The meeting Agenda 
|
Funded under Horizon 2020 project - SupraChem Lab - Laboratory of Supramolecular Chemistry for Adaptive Delivery Systems - ERA Chair initiative
Dr. Sinda Lepetre-Mouelhi - Associate Professor at Institut Galien (Paris-Sud University) France: she works in the team of Prof. Patrick Couvreur. She obtained a Master Degree in "Heterochemistry, Catalysis and Polymers" in 1997 at the Faculty of Sciences of Montpellier 2 (France), and completed her PhD in Organic Chemistry in 2002 under the supervision of Prof. M. Bellassoued at the University of Cergy-Pontoise (France). During her thesis she developped a new direct access route to (E)-a,?-ethylenic acids via a trisilylated building block. After her thesis, she was recruited by the UN for a mission in Kosovo as International Trainer for 18 months. In 2003, she started her first post-doctoral internship in Medicinal Chemistry at the Faculty of Pharmacy of Châtenay-Malabry (BioCIS-UMR 8076) with Prof. S. Sicsic. Then, in 2004, she worked during a few months at Sanofi-Aventis in Chilly-Mazarin in the medicinal chemistry field. In 2005 she joined the group of Prof. Patrick Couvreur as a post-doctoral researcher in Therapeutic Chemistry and Formulation at Institut Galien and got an Associate Professor position. She currently (co-)directs 3 teaching units: UE120, UE294, UE19. Her current research activity lies in the synthesis of squalene-based bioconjugates and their formulation into nanoparticles. The main fields of application include cancer, HIV, and more recently, cerebral and hepatic ischemia, as well as pain. She is co-author of 35 peer review articles in international journals and one book chapter. 
In 2010 he became managing director of the Institute for Polymer Technology at the Bergische Universität. Since 1999 he has also received four additional calls, which he did not accept. In 2011, Scherf was ranked 26th in the global Top 100 Material Scientists ranking by Thomson Reuters. In 2012, a project by Scherfs on research on the stability of organic solar cells, which he carried out in cooperation with the universities of Tübingen, Würzburg and Munich, was named Project of the Month by the Federal Ministry of Education and Research. 
During the afternoon all the SupraChem Lab group together with the trainers have moved to a specialised hosting facility for team building events were the second two days of training and teambuilding took place. The idea of this modified program was to isolate the group from their daily home duties and put them together for two days to increase interaction with the group and with the trainers. Thus, the teambuilding event was a wonderful opportunity to learn mor about each others not only a about science – see left side PhD student Radu Zonda singing for all the team. 
Associate Scientist, Department of Oncology Mount Sinai School of Medicine, 2008; Assistant Research Scientist Skirball Institute, New York University School of Medicine, 2006; Postdoctoral Associate, Brookdale Department of Molecular, Cell & Developmental Biology Mount Sinai School of Medicine, 2003; Biochemistry Ph.D. - 2002 
Prof. Claudiu Supuran, Unversity of Florence and member of the SupraChem Lab IAB has presented a two days traning on Carbonic Anhydrase Inhibitors As Emerging Agents For The Treatment And Imaging Of Hypoxic Tumors. Prof. Claudiu T. Supuran is professor of medicinal and pharmaceutical chemistry at the University of Florence, Italy, since 1995. He did his Ph D at University of Bucharest, Romania, and was a visiting scholar at University of Florida, Gainesville, USA, and at Grifitth University, Brisbane, Australia. He was visiting professor at University of La Plata, Argentina and at University of New South Wales, Sydney, Australia. His main research interest is the medicinal chemistry/biochemistry of carbonic anhydrases, field in which he has made contributions to the design of many novel classes of enzyme inhibitors and activators, deciphering their mechanism of action at molecular level, discovery of new isoforms and their role in disease (cancer, obesity, epilepsy, neuropathic pain and cognition), discovery and characterization of carbonic anhydrases from various organisms (bacteria, fungi, corals, vertebrates other than humans and rodents, etc). Other research interests include X-ray crystallography of metallo-enzymes, heterocyclic chemistry, chemistry of sulfonamides, metal-based drugs, cyclooxygenases, serine proteases, matrix metalloproteinases, bacterial proteases, and amino acid derivatives among others. He has published more than 1500 papers in these fields and his Hirsch index is 134. One of the compounds discovered in his laboratory (SLC-0111) is in Phase II clinical trials for the treatment of advanced metastatic solid tumors 
Training on 2,3-exo-Diheterotactic Dicyclopentadiene Oligomers: An X-ray Powder Diffraction Study of a Challenging Multiphase Case 
Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden: Research interests in general: Bio & Materials modeling/simulation across long time/length scales; Method development: first-principles, atomistic simulations and coarse-grained modeling. Research interests in DNA: structure, dynamics, hydration, manipulation, damage and repair.Computer simulations of DNA (MD & MC) since 1983. 
