Dr. Natalia SIMIONESCU
PhD, Researcher
Specialization
BIOLOGIST
Description
Biological activity of natural and synthetic compounds. MicroRNAs as biomarkers for diseases severity and progression. Biocompatibility of medical devices, cytotoxicity of polymeric materials and conjugates designed for cancer therapy. Lactic acid bacteria fermentations; extraction, purification and characterization of exopolysaccharides; probiotic and prebiotic properties of lactic acid bacteria fermentations. Cell cultures, molecular biology, biochemical assays, ELISA, optimizing and adapting biochemical and cellular assays, managing databases and biostatistics.
Contact
+40 332 880 050 – 516
Curiculum Vitae
Publications List
| No. | Publications | DOI | YEAR | Citations |
|---|---|---|---|---|
| 1. | Petrovici, A.R.; Pinteala, M.; Simionescu, N. Dextran Formulations as Effective Delivery Systems of Therapeutic Agents. Molecules, 2023, 28, 1086. | 10.3390/molecules28031086 | 2023 | 0 |
| 2. | Simionescu, N.; Nemecz, M.; Petrovici, A.-R.; Nechifor, I.S.; Buga, R.-C.; Dabija, M.G.; Eva, L.; Georgescu, A. Microvesicles and Microvesicle-Associated microRNAs Reflect Glioblastoma Regression: Microvesicle-Associated miR-625-5p Has Biomarker Potential. Int. J. Mol. Sci., 2022, 23, 8398. | 10.3390/ijms23158398 | 2022 | 1 |
| 3. | Ghiarasim, R.; Simionescu, N.; Coroaba, A.; Uritu, C.M.; Marangoci, N.L.; Ibanescu, S.-A.; Pinteala, M. SI-ATRP Decoration of Magnetic Nanoparticles with PHEMA and Post-Polymerization Modification with Folic Acid for Tumor Cells’ Specific Targeting. Int. J. Mol. Sci., 2022, 23, 155. | 10.3390/ijms23010155 | 2022 | 1 |
| 4. | Simionescu, N.; Zonda, R.; Petrovici, A.R.; Georgescu, A. The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy. Pharmaceutics, 2021, 13, 988. | 10.3390/pharmaceutics13070988 | 2021 | 5 |
| 5. | Petrovici, A.R.; Simionescu, N.; Sandu, A.I.; Paraschiv, V.; Silion, M.; Pinteala, M. New Insights on Hemp Oil Enriched in Cannabidiol: Decarboxylation, Antioxidant Properties and In Vitro Anticancer Effect. Antioxidants, 2021, 10, 738. | 10.3390/antiox10050738 | 2021 | 14 |