Dr. Bogdan Florin CRACIUN

Research Assistant

Specialization

CHEMIST

Description

Research assistant at PPMIC, specialized in organic synthesis as well as the procedures required to purify and characterize the chemical compounds (e.g. NMR, FTIR, UV-Vis, Fluorescence). He also has experience with drug and genetic material delivery systems obtained through Dynamic Chemistry, as well as a thorough understanding of all the techniques used to characterize macromolecular and supramolecular systems, from structural (e.g. NMR, FTIR, UV-VIS, SAX, DRX, XPS, CD) to morphological (e.g. AFM, TEM, SEM, DLS) and biological assessments (e.g. Gel Electrophoresis, controlled release of drugs). His scientific contribution is emphasized by 10 ISI articles, one book chapter, and an H-index of 5 (WoS), 5 (Google), and 6 (Scopus). During his research career, he was a member in 12 national/international grants implementation teams and director of a Post-Doctoral Research Project.

Contact

+40 332 880 050 – 554

Curiculum Vitae
Publications List
No.PublicationsDOIYEARCitations
1.Crӑciun, B.F.; Clima, L.; Boștiog, D.I.; Silion, M.; Calin, M.; Peptanariu, D.; Pintealӑ, M.; Multilayer Gold nanoparticles as non-viral vectors for targeting MCF-7 cancer cells; Biomaterials Advances, 2023, 144, 213201.10.1016/j.bioadv.2022.21320120231
2.Vasiliu, T.; Craciun, B.F.; Neamtu, A.; Clima, L.; Isac, D.L.; Maier, S.S.; Pinteala, M.; Mocci, F. and Laaksonen A.; In silico study of PEI-PEG-squalene-dsDNA polyplex formation: the delicate role of the PEG length in the binding of PEI to DNA; Biomater. Sci., 2021, 9, 6623-6640.10.1039/D1BM00973G20215
3.Clima, L.; Craciun, B.F.; Angeli, A.; Petreni, A.; Bonardi, A.; Nocentini, A.; Carta, F.; Gratteri, P.; Pinteala, M. and Supuran, C.T.; Synthesis, computational studies and assessment of in vitro activity of squalene derivatives as carbonic anhydrase inhibitors; ChemMedChem, 2020, 15, 2052.10.1002/cmdc.20200050020202
4.Clima, L.; Craciun, B.F.; Gavril, G.; Pinteala, M. Tunable Composition of Dynamic Non-Viral Vectors over the DNA Polyplex Formation and Nucleic Acid Transfection. Polymers201911, 1313.10.3390/polym1108131320199
5.Craciun, B.F.; Gavril, G.; Peptanariu, D.; Ursu, L.E.; Clima, L.; Pinteala, M. Synergistic Effect of Low Molecular Weight Polyethylenimine and Polyethylene Glycol Components in Dynamic Nonviral Vector Structure, Toxicity, and Transfection Efficiency. Molecules201924, 1460.10.1021/acssuschemeng.8b00331201916
6.Crăciun, B.F.; Vasiliu, T.; Marangoci, N.; Pinteală, M. and Clima, L.; PEGylated Squalene: a biocompatible polymer as precursor for drug delivery; Rev. Roum. Chim., 2018, 63, 621-628.nos-7-8-201820185