Objectives

     

 

     The STRATEGIC OBJECTIVE of Dynamic Constitutional Platforms for Targeted Drug Delivery (DynaCoPlat) project is the formation and consolidation of a young multidisciplinary team of researchers within PPIMC with complementary knowledge and experience in order to:

• create a synergetic effect to the proposed research field and contribute to translational research having the potential to advance the applied nanomedical sciences;
• educate competitive experts at national and international level with high impact on academic, economic and health environment;
• increase the capability of young researcher to develop and implement independent research;
• increase the scientific visibility publishing the results in high impact journals, applying to national and European competitions (H2020, Era-Net, Euronanomed, etc.).

     THE MAIN SCIENTIFIC OBJECTIVE of the DynaCoPlat proposal is to create dynamic nanoplatforms  (nano-frameworks and nanostructures) for developing dynamic systems for enhanced multivalent biorecognition with applications in targeted drug delivery. This project proposes to combine newly established dynamic chemistry and combinatorial approach for the formation of large libraries of compounds (DCPs) developed by us on one hand and introduction of targeting specificity to the DCPs on the other hand. The strategy is based on the construction of materials from linear and/or crosslinked arrays that are bound through reversible bonds and able to respond to internal or external factors by components’ exchange.